Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH_Pat89 | ESH427 | Uganda | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10IV, I13V, G16E, K20R, E35D, M36I, R41K, R57K, H69K, K70R, L89M |
| >ESH427| codons 1-99 PQITLWQRPIVTVKIEGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11T, K20R, V21I, V35T, T39KR, K43KR, D121DN, K122E, D123S, K173S, D177G, V179I, T200A, I202V, Q207A, R211RS, V245Q, E248D, V276VI, K277R, T286A, E291D, V292I, I293V, P294T, E312ED |
| >ESH427| codons 1-334 PISPIETVPVTLKPGMDGPRIKQWPLTEEKIKALTEICKEMEREGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL NESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPGIII YQYMDDLYVGSDLEIGQHRAKVEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKIRQLCKLLRGAKALTDIVTLTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Eshleman, SH | Characterization of nevirapine resistance mutations in women with subtype A vs. D HIV-1 6-8 weeks after single-dose nevirapine. | JAIDS, 2004 |