Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH_Pat72 | ESH708 | Uganda | 1998 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, N37D, R41K, R57RK, D60E, L63P, I64V, K70KR, I72L |
| >ESH708| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDMDLPGKWKPKMIGGIGGFIKVKQYE QIPVEICGHRALGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| A33AV, V35T, K49R, V60I, K122E, D123DG, D177E, I178M, T200K, Q207E, R211K, V245X, D250E, A272P, I274IV, K275R, L282C, R284RK, T286A, I293V, E297K, I309IL, V317VA |
| >ESH708| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKVLTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYMDDLYVGSDLEIGQHRKKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIXLPEKESWTVNDIQKLVGKLNWASQIYPGVRVKQLCKCLKGAKALTEVVPLTKEAE LELAENRELLKEPVHGAYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Eshleman, SH | Characterization of nevirapine resistance mutations in women with subtype A vs. D HIV-1 6-8 weeks after single-dose nevirapine. | JAIDS, 2004 |