Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH_Pat24 | ESH46 | Uganda | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20R, V35T, E40ED, K49R, K122E, D123N, I135T, K173S, Q174QK, V179I, Q207A, R211S, V245Q, E291D, I293V, P294T, L295LM, E312D |
| >ESH46| codons 1-334 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTDMEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPDIII YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDVVTMTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, R57K, L63C, H69K, L89M |
| >ESH46| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QICIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Eshleman, SH | Characterization of nevirapine resistance mutations in women with subtype A vs. D HIV-1 6-8 weeks after single-dose nevirapine. | JAIDS, 2004 |