Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat42 | BR02SP154 | Brazil | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ AZT | 21 |
| 2 | RTV+ 3TC+ AZT | 13 |
| 3 | 3TC+ AZT+ EFV | 21 |
| 4 | Unknown | NA |
| 5 | NFV+ 3TC+ AZT+ EFV | 57 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V | T215D | L100I, K103N | V35T, E169D, K173T, Q174K, T200A, Q207D, R211K, V245Q, E248D, T286A, E291D, V292I, I293V, E297A |
| >BR02SP154| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRTKNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFDTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | T12R, I15V, L19S, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, T74S, V77I, L89M, I93IL |
| >BR02SP154| codons 1-99 PQITLWQRPLVRIKVGGQSTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD NVLIEICGHKAIGSVLIGPTPVNIIGRNMMTQLGCTLNF |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |