Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat41 | BR02SP138 | Brazil | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ AZT | 8 |
| 2 | DDI | 30 |
| 3 | 3TC+ AZT | 186 |
| 4 | Unknown | NA |
| 5 | NFV+ D4T+ 3TC | 11 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46ML | N88D | L10V, I13V, I15V, K20R, E35D, M36I, N37NI, R41K, K45KR, R57K, Q61D, A71T, I72T |
| >BR02SP138| codons 1-99 PQITLWQRPVVTVKVGGQLREALLDTGADNTVLEDIILPGKWKPRLIGGIGGFIKVKQYD DILIEICGHKTTGTVLVGPTPVNIIGRDLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, T215Y | E6D, K20R, V35T, T39A, K43Q, E44D, K49R, V118I, K122E, I135V, S162C, E169D, K173A, Q174K, I178L, E203A, Q207E, H208Y, R211K, K223Q, L228Q, V245Q, E248DN, D250DE, A272P, T286A, E291D, V292I, I293V, P294T, E297A |
| >BR02SP138| codons 1-335 PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALTEICAELEQDGKISRIGPENPYNTPV FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDLVI YQYVDDLYVGSDLEIGQHRTKIAELREYLLKWGFYTPDKKHQQEPPFQWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |