<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BLF_Pat39 BR02SP241 Brazil 2002 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 IDV+ 3TC+ AZT 17
2 3TC+ AZT+ NVP 34
3 NFV+ D4T+ 3TC 124

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N V108I V35T, T39M, I135V, E169D, K173T, Q174K, E194EG, G196E, T200A, Q207D, R211K, F214L, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297A, K311R, S322T  
>BR02SP241| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICMEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRTKNPDIVI
YQYVDDLYVGSDLGIEQHRAKIEELRDHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE
LELAENREILREPVHGVYYDPTKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
N88S   L10V, I15V, K20T, E35D, M36I, R57K, Q61D, I72R, L89M, I93L  
>BR02SP241| codons 1-99
PQITLWQRPVVTIKVGGQLTEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYD
DILIEICGHKARGTVLVGPTPVNIIGRSMLTQLGCTLNF

References
Author Title Citation
Rodrigues, R Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. J Clin Virol, 2005