Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat38 | BR03SP211 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ AZT+ NVP | 52 |
| 2 | RTV+ IDV+ D4T+ 3TC | 52 |
| 3 | D4T+ 3TC+ NVP | 99 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, T215F | L100I, K103N | K20R, V35T, T39S, K122E, E169D, K173A, Q174K, D177DG, T200A, E203K, Q207E, H208Y, R211K, K223E, L228R, V245Q, E248D, A272P, E291D, V292I, I293V, E297A, I326V, I329V |
| >BR03SP211| codons 1-335 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICSELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRAKNPGIVI YQYVDDLYVGSDLEIGQHRAKIKELREYLLKWGFFTPDKKHQEEPPFRWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLVAEVQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, H69Y, I72T, L89M |
| >BR03SP211| codons 1-99 PQITLWQRPVVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD NILIEICGYKATGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |