Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat37 | BR03SP90 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ DDI | 43 |
| 2 | IDV+ D4T+ 3TC | 39 |
| 3 | RTV+ D4T+ 3TC | 30 |
| 4 | SQV+ 3TC+ AZT | 39 |
| 5 | Unknown | NA |
| 6 | D4T+ DDI+ LPV | 23 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, E35D, M36I, R41K, K45R, R57K, D60E, Q61N, E65D, I72T, L89M |
| >BR03SP90| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYE NILIDICGHKATGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V | K103N | E6EK, V35T, K49R, I50V, K122E, D123E, I135V, S162C, E169D, K173A, Q174K, T200A, Q207E, R211K, V245Q, E248D, A272P, T286A, E291D, I293V, E297A, G333E |
| >BR03SP90| codons 1-335 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRVGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDVVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQEQG |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |