<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BLF_Pat36 BR02SP117 Brazil 2002 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ 3TC 39
2 D4T+ 3TC+ EFV 52
3 D4T+ 3TC+ NVP 9

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74IV, M184V, T215Y   K103N, Y181C, G190A   K20R, V35I, T39K, K43E, K49R, V118I, I142V, S162D, E169D, K173A, Q174K, G196E, T200A, E203D, Q207K, H208Y, R211A, H221Y, V245Q, E248D, A272P, T286A, A288T, E291D, V292I, I293V, E297T, I329L  
>BR02SP117| codons 1-335
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICKELEEEGKISRIGPENPYNTPV
FAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQDSMTKILDPFRAKNPDIVI
CQYVDDLYVASDLEIEQHRAKIDELRKYLLAWGFYTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKTLTDIVPLTTEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, T12I, I15V, G16E, E35D, M36I, P39PQ, R41K, R57K, D60E, Q61N, L63C, I72T, L89M  
>BR02SP117| codons 1-99
PQITLWQRPVVIIKVEGQLKEALLDTGADDTVLEDINLQGKWKPKMIGGIGGFIKVKQYE
NICIEICGHKATGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Rodrigues, R Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. J Clin Virol, 2005