Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat33 | BR03SP36 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | SQV+ 3TC+ AZT | 13 |
| 2 | 3TC+ AZT | 43 |
| 3 | DDI+ AZT+ NVP | 35 |
| 4 | NFV+ D4T+ DDI | 73 |
| 5 | IDV+ 3TC+ AZT | 43 |
| 6 | 3TC+ AZT+ EFV | 41 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219E | K101E, Y181C, G190A | V108I | E6D, K20R, V35T, T39L, V60I, V90I, I135R, S162H, E169D, K173A, Q174K, V179I, T200R, Q207E, R211K, L228H, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294S, E297A |
| >BR03SP36| codons 1-335 PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALTEICLEMEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEIQLGIPHPAGLEKKKSVTILDVGDAYFSVPL DKDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQHSMTKILDPFRAKNPDIII CQYVDDLYVASDLEIGQHRRKIEELREHLLKWGFFTPDEKHQKEPPFHWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVSLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L | L10F, N88T | K14R, I15V, K20T, E35N, M36I, R41K, R57K, Q61N, I72V, L89M |
| >BR03SP36| codons 1-99 PQITLWQRPFVTIRVGGQLTEALLDTGADDTVLENINLPGKWKPKLIGGIGGFIKVKQYD NILIEICGHKAVGTVLVGPTPVNIIGRTMLTQIGCTLNF |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |