Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat32 | BR02SP56 | Brazil | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV+ 3TC+ AZT | 208 |
| 2 | IDV+ D4T+ 3TC | 82 |
| 3 | Unknown | NA |
| 4 | NFV+ D4T+ DDI+ NVP | 4 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, M184V, L210W, T215Y | K103KN, Y181C | K32I, V35T, T39S, K49R, V118I, K122E, D123E, I135V, K173T, Q174K, I178M, T200TA, Q207E, R211K, V245Q, E248D, A272P, Q278H, T286P, E291D, V292I, I293V, P294T, E297A, S322T, Q334N |
| >BR02SP56| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIIALTEICSELEKEGKISRIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DEEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDMVI CQYVDDLYVGSDLEIGQHRAKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGPKALTDIVTLTAEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGNG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82L, L90M | K43T | L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, L89M, I93L |
| >BR02SP56| codons 9-99 PVVTIKVGGQLREALLDTGADDTVLEDINLPGKWTPKMIGGIGGFIKVKQYDNIPIEICG HKAIGTVLVGPTPLNIIGRNMMTQLGCTLNF |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |