Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat31 | BR03SP35 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ 3TC | 113 |
| 2 | NFV+ D4T+ 3TC | 12 |
| 3 | RTV+ D4T+ 3TC | 21 |
| 4 | D4T+ 3TC+ EFV | 119 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12N, I15V, E35D, M36I, R41K, R57K, Q61N, L63V, V82I, L89M |
| >BR03SP35| codons 1-99 PQITLWQRPLVNIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD NIVIEICGHKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215Y | K101P, K103N | K20R, E28K, V35T, D123E, E169D, K173A, Q174K, T200A, Q207E, R211K, V245Q, E248N, D250E, A272P, T286V, E291D, V292I, I293V, E297T, V317A |
| >BR03SP35| codons 1-335 PISPIETVPVKLKPGMDGPRVKQWPLTKEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLPKNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRAKNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPNKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGVKALTDIVPLTTEAE LELAENREILKEPVHGAYYDPSKDLIAEIQKQGQG |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |