Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat30 | BR03SP179 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ DDI+ AZT | 95 |
| 2 | RTV+ IDV+ D4T+ 3TC | 4 |
| 3 | Unknown | NA |
| 4 | D4T+ 3TC+ NVP | 34 |
| 5 | RTV+ 3TC+ AZT+ APV | 4 |
| 6 | APV+ RTV+ 3TC+ AZT+ LPV | 8 |
| 7 | Unknown | NA |
| 8 | NFV+ 3TC+ AZT | 41 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13IV, E35D, M36I, R41K, R57K, D60E, Q61N, I72IT, V77I, L89M |
| >BR03SP179| codons 1-99 PQITLWQRPVVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE NILIEICGHKATGTVLIGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39X, K122KE, D123E, I135V, S162C, E169ED, K173A, Q174K, D177E, I178L, T200A, Q207D, R211K, T215X, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294PT, E297V |
| >BR03SP179| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICXEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPELVI YQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFXTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTVEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |