Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat29 | BR03SP247 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ AZT | 82 |
| 2 | Unknown | NA |
| 3 | NFV+ D4T+ 3TC | 60 |
| 4 | D4T+ 3TC+ NVP | 52 |
| 5 | RTV+ SQV+ DDI+ AZT | 28 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | N83D | L10I, I15V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63T, I72T, L89M, I93L |
| >BR03SP247| codons 1-99 PQITLWQRPIVTIKVEGQLREALLDTGADDTVLEDINLPGKWKPRMIGGIGGFVKVKQYD NITIEICGHKATGTVLVGPTPADIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T215Y | K101E, Y181I | E6K, V35MR, T39A, K122E, S162D, F171Y, K173T, Q174K, E203K, Q207E, R211K, K223Q, A272P, K277R, L283I, T286A, E291D, V292I, I293V, E297A, V317A, G333E, Q334Y |
| >BR03SP247| codons 1-335 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAELEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPYRTKNPDIVI IQYMDDLYVGSDLEIGQHRTKIKELREHLLKWGFYTPDKKHQQEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGAKALTDIVPLTAEAE LELAENREILKEPVHGAYYDPSKDLIAEIQKQEYG |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |