<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BLF_Pat27 BR03SP155 Brazil 2003 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 NFV+ DDI+ AZT 35

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
N88S   L10V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, E65D, L89M  
>BR03SP155| codons 1-99
PQITLWQRPVVTIKVGGQLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
NIPIDICGHKAIGTVLVGPTPVNIIGRSMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       K20R, V35T, T39M, K122E, I135V, E138A, S162C, K173A, Q174R, G196E, Q207D, R211K, F214L, V245Q, E248D, D250E, A272P, V276I, T286A, E291D, V292I, I293V, P294T, E297T, I329L  
>BR03SP155| codons 1-335
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICMEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSVNNATPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRARNPDIVI
YQYVDDLYVGSDLEIEQHRTKIEELRDHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGAKALTDIVTLTTEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGQG

References
Author Title Citation
Rodrigues, R Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. J Clin Virol, 2005