Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat25 | BR02SP184 | Brazil | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV+ D4T+ 3TC | 113 |
| 2 | DDI+ AZT | 108 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | S3R, E6D, E28K, K32E, V35T, T39M, K49R, I135V, S162C, E169D, K173A, Q174K, I178L, T200K, E203D, Q207A, R211Q, V245Q, E248D, A272P, K277R, T286A, V292I, I293V, E297T, I329L |
| >BR02SP184| codons 1-335 PIRPIDTVPVKLKPGMDGPKVKQWPLTKEKIEALTEICMEMEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDLVI YQYVDDLYVGSDLEIGQHRKKIDELRAHLLQWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEIVPLTTEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L10V, I15V, K20R, E35D, M36I, P39Q, R41K, R57K, Q61N, I62V, L63A, T74S, L89M |
| >BR02SP184| codons 1-99 PQITLWQRPVVTIKVGGQLREALLDTGADDTVLEDINLQGKWKPKMIGGIGGFIKVKQYD NVAIEICGHKAIGSVLVGPTPVNIIGRNMMTQIGCTLNF |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |