Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat24 | BR02SP255 | Brazil | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 17 |
| 2 | DDI+ AZT | 65 |
| 3 | IDV+ 3TC+ AZT | 95 |
| 4 | RTV+ SQV+ D4T+ 3TC | 82 |
| 5 | NFV+ D4T+ 3TC+ NVP | 71 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, G48V, I54T, V82A | L10I, I15V, L19LI, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, C67D, A71V, I72T, I93L |
| >BR02SP255| codons 1-99 PQITLWQRPIVTIKVGGQIREALLDTGADDTVLEDINLPGKWKPKIIVGIGGFTKVKQYD NIPIEIDGHKVTGTVLVGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | K101E, Y181C, G190A | V35T, T39PS, K43N, E44D, V118I, K122E, I135V, S162Y, K173T, Q174K, N175Y, T200A, E203K, Q207D, R211K, K223Q, V245Q, E248D, T286A, A288T, V292I, I293V, E297A, Q334E |
| >BR02SP255| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICPELENDGKISKIGPENPYNTPV FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRTKYPDIVI CQYVDDLYVASDLEIGQHRAKIKELRDHLWKWGFYTPDKKHQQEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKTLTEIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEG |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |