Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat23 | BR03SP224 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ DDI+ NVP | 52 |
| 2 | Unknown | NA |
| 3 | RTV+ D4T+ 3TC+ APV | 4 |
| 4 | Unknown | 78 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I50V, I54V, V82A, L90M | L23I, F53L, L76M | L10I, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63A, I64M, L89M, I93L |
| >BR03SP224| codons 1-99 PQITLWQRPIVTIKVGGQLREAILDTGADDTVLEDINLPGKWKPRIIGGVGGLVKVKQYD NIAMEICGHKAIGTVMVGPTPANIIGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215SY | K219EQ | V35T, T39M, I135V, S162C, K166R, E169D, K173T, Q174K, Q207E, K223KE, L228LH, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297V, V317A, I329L |
| >BR03SP224| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICMEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTRILDPFRTKNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELREHLLRWGFSTPDEKHQEEPPFHWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTVEAE LELAENREILKEPVHGAYYDPSKDLIAELQKQGQG |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |