Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat20 | BR03SP220 | Brazil | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ AZT | 30 |
| 2 | 3TC+ AZT | 30 |
| 3 | Unknown | NA |
| 4 | NFV+ D4T+ 3TC | 173 |
| 5 | DDI+ AZT+ EFV | 18 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63LP, E65D, T74S, L89M |
| >BR03SP220| codons 1-99 PQITLWQRPVVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD NVPIDICGHKAIGSVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, V75M, T215F | K219Q | K103N | V179E, K238T | V35T, T39TI, V60I, T69N, K122E, D123S, E138Q, E169D, K173A, Q174K, I178L, T200A, H208Y, R211A, D218DE, V245Q, E248D, A272P, T286A, A288T, E291D, V292I, I293V, E297A, I329L |
| >BR03SP220| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICIELEKEGKISKIGPENPYNTPI FAIKKKNSNRWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNQTPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRAKNPDLEI YQYMDDLYVGSDLEIGQHRAKIEELRQYLLAWGFFTPEQKHQKEPPFLWMGYELHPDTWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKTLTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGQG |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |