Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat16 | BR03SP111 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 4 |
| 2 | DDI+ AZT | 47 |
| 3 | SQV+ 3TC+ AZT | 113 |
| 4 | IDV+ 3TC+ AZT | 34 |
| 5 | NFV+ 3TC+ AZT | 146 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, M184V, T215Y | K219E | V35MT, K43E, E44A, T107S, L109I, D123E, S162C, K173A, Q174K, D177E, T200A, E203D, Q207D, H208Y, R211K, W212L, H221Y, L228H, V245Q, E248D, S251D, A272P, T286A, E291D, V292I, I293V, E297T, V317A, Q334C |
| >BR03SP111| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICTELEEAGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVSVIDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAKNPEIVI YQYVDDLYVGSDLEIGQHRAKIDELRDYLLKLGFYTPDEKYQKEPPFHWMGYELHPDKWT VQPIQLPDKDDWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTTEAE LELAENREILKEPVHGAYYDPSKDLIAEIQKQGCG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | L10I, I13V, I15V, K20R, E35D, M36V, N37NS, R41K, R57K, Q61N, I62IV, L63LP, E65D, A71I, I72T |
| >BR03SP111| codons 1-99 PQITLWQRPIVTVKVGGQLREALLDTGADNTVLEDVSLPGKWKPKMIGGIGGFIKVKQYD NVPIDICGHKITGTVLVGPTPVNIIGRDLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |