Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat14 | BR02SP108 | Brazil | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ AZT | 91 |
| 2 | SQV+ DDI+ AZT | 147 |
| 3 | IDV+ 3TC+ AZT | 47 |
| 4 | D4T+ DDI+ EFV | 34 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K219E | V106M, Y188L | E6D, K20R, V35M, T39TA, V60I, G141GA, S162Y, K173T, Q174K, Q207E, H208Y, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294S, E297A |
| >BR02SP108| codons 1-335 PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALMEICAEMEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPAIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRTKNPDIVI YQYMDDLLVGSDLEIGQHRTKIEELREYLLKWGFFTPDEKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVSLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, E35ED, M36I, R41K, R57RK, Q61N, I62V, L63LP, I72IV, T74S, L89M |
| >BR02SP108| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD NVPIEICGHKAVGSVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |