<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BLF_Pat14 BR02SP108 Brazil 2002 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ AZT 91
2 SQV+ DDI+ AZT 147
3 IDV+ 3TC+ AZT 47
4 D4T+ DDI+ EFV 34

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, E35ED, M36I, R41K, R57RK, Q61N, I62V, L63LP, I72IV, T74S, L89M  
>BR02SP108| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
NVPIEICGHKAVGSVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, T215F K219E V106M, Y188L   E6D, K20R, V35M, T39TA, V60I, G141GA, S162Y, K173T, Q174K, Q207E, H208Y, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294S, E297A  
>BR02SP108| codons 1-335
PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALMEICAEMEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPAIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRTKNPDIVI
YQYMDDLLVGSDLEIGQHRTKIEELREYLLKWGFFTPDEKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVSLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG

References
Author Title Citation
Rodrigues, R Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. J Clin Virol, 2005