Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat11 | BR03SP43 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ IDV | 39 |
| 2 | Unknown | NA |
| 3 | 3TC+ D4T+ IDV | 39 |
| 4 | 3TC+ D4T+ SQV+ RTV | 82 |
| 5 | EFV+ AZT+ DDI+ NFV | 30 |
| 6 | EFV+ 3TC+ D4T+ IDV | 26 |
| 7 | NVP+ AZT+ 3TC+ IDV+ RTV | 30 |
| 8 | Unknown | 20 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215F | K101P, K103N | P4T, K20KR, E28K, K32E, V35T, K49R, V60I, I135V, S162C, E169D, K173A, Q174K, T200A, Q207E, R211K, L228H, V245Q, E248D, A272P, T286A, I293V, E297T |
| >BR03SP43| codons 1-335 PISTIETVPVKLKPGMDGPRVKQWPLTKEKIEALTEICTELEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLPKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFFTPDKKHQKEPPFHWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVPLTTEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | T12M, I15V, L19I, K20R, E35D, M36I, N37D, R41K, R57K, Q61H, I62V, H69R, T74S, L89I, C95CF |
| >BR03SP43| codons 1-99 PQITLWQRPLVMIKVGGQIREALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFVKVKQYD HVLIEICGRKAIGSVLVGPTPANIIGRNIMTQIGFTLNF |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |