Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat9 | BR03SP182 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 52 |
| 2 | DDI | 26 |
| 3 | DDI+ AZT | 17 |
| 4 | RTV+ DDC+ D4T | 8 |
| 5 | RTV+ D4T+ 3TC | 217 |
| 6 | SQV+ NFV+ EFV+ DDI+ D4T | 94 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69DE, K70R | K219Q | Y181YC, G190GA | K101H, K238KT | P14PS, K20R, V35T, T39M, V60I, K103KR, V118VI, D123E, I135T, S162Y, K173T, Q174K, E203K, R211T, F214L, D218E, L228H, Q242X, V245Q, E248D, A272P, K275R, Q278N, T286A, A288T, E291D, V292I, I293V, E297A, V317A, S322T, D324E | Q269QH |
| >BR03SP182| codons 1-335 PISPIETVPVKLKSGMDGPRVKQWPLTEEKIKALTEICMEMEKEGKISKIGPENPYNTPI FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLHKRKSVTVLDVGDAYFSIPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRTKNPDIVI CQYMDDLYVASDLEIGQHRTKIKELRQHLLTWGLTTPEQKHQKEPPFHWMGYELHPDTWT VXPIQLPDKDSWTVNDIQKLVGKLNWASHIYPGIRVKNLCKLLRGAKTLTDIVPLTAEAE LELAENREILKEPVHGAYYDPTKELIAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | L10I, I13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71AT |
| >BR03SP182| codons 1-99 PQITLWQRPIVTVKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVKQYD NIPIEICGHKTIGTVLVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |