<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BLF_Pat5 BR03SP147 Brazil 2003 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 Unknown NA
2 3TC+ IDV+ D4T 256

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A   L10I, I13V, I15V, G17E, K20I, E35D, M36I, R41K, R57K, Q61N, L63R, E65D, T74S, L89I  
>BR03SP147| codons 1-99
PQITLWQRPIVTVKVGEQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVKQYD
NIRIDICGHKAIGSVLVGPTPANIIGRNILTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, M184V, T215Y       K20KR, V35T, T39M, S48T, K49R, D123E, I135V, S162C, E169D, K173T, Q174K, I178L, V179I, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, Q278H, T286A, E291D, V292I, I293V, P294S, E297A  
>BR03SP147| codons 1-335
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICMELEKEGKITRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRTKNPDLII
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGAKALTDIVSLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG

References
Author Title Citation
Rodrigues, R Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. J Clin Virol, 2005