Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat4 | BR02SP265 | Brazil | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ DDI | 143 |
| 2 | 3TC+ NVP+ D4T | 40 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | A62AV, K70NS, V75I, F77L, F116Y | K103N, Y181C | E6S, K20R, V21VI, V35T, T39A, K64R, S68G, K122E, S162SC, E169D, K173A, Q174K, I178L, G196E, T200A, Q207E, R211K, H221Y, V245Q, E248N, A272P, T286A, E291D, V292I, I293V, E297V, V317A |
| >BR02SP265| codons 1-335 PISPISTVPVKLKPGMDGPRIKQWPLTEEKIKALTEICAEMEKEGKISKIGPENPYNTPV FVIRKKDGTNWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYYSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQCSMTKILDPFRAKNPDLVI CQYVDDLYVGSDLEIEQHRAKIEELREHLLKWGFTTPDKKYQKEPPFLWMGYELHPDKWT VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTVEAE LELAENREILKEPVHGAYYDPSKDLIAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15V, K20R, M36I, R41K, R57K, Q61S, I72V |
| >BR02SP265| codons 1-99 PQITLWQRPLVTVKVGGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVKQYD SILIEICGHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |