Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BLF_Pat3 | BR02SP249 | Brazil | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ AZT+ NVP | 108 |
| 2 | Unknown | NA |
| 3 | 3TC+ NFV+ AZT | 74 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | Y181C | V108I | L34I, V35T, K49R, I135V, S162C, E169D, K173A, Q174K, T200I, Q207E, R211K, H221Y, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297T, K311R |
| >BR02SP249| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKAITEICTELEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDIVI CQYVDDLYVGSDLEIGQHRIKIEELREHLWKWGFYTPDKKYQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTTEAE LELAENREILREPVHGVYYDPSKDLIAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N88S | K20T, E35D, M36I, R41K, R57K, Q61N, V77I, L89M |
| >BR02SP249| codons 1-99 PQITLWQRPLVTIKIGGQLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD NILIEICGHKAIGTVLIGPTPVNIIGRSMLTQIGCTLNF |
References
| Author | Title | Citation |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |