<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BLF_Pat3 BR02SP249 Brazil 2002 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ AZT+ NVP 108
2 Unknown NA
3 3TC+ NFV+ AZT 74

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
N88S   K20T, E35D, M36I, R41K, R57K, Q61N, V77I, L89M  
>BR02SP249| codons 1-99
PQITLWQRPLVTIKIGGQLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
NILIEICGHKAIGTVLIGPTPVNIIGRSMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215Y   Y181C V108I L34I, V35T, K49R, I135V, S162C, E169D, K173A, Q174K, T200I, Q207E, R211K, H221Y, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297T, K311R  
>BR02SP249| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKAITEICTELEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDIVI
CQYVDDLYVGSDLEIGQHRIKIEELREHLWKWGFYTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTTEAE
LELAENREILREPVHGVYYDPSKDLIAEIQKQGQG

References
Author Title Citation
Rodrigues, R Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. J Clin Virol, 2005