<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BLF_Pat1 BR03SP230 Brazil 2003 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ AZT 52
2 IDV+ 3TC+ AZT 47
3 Unknown 100

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12A, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63A, L89M  
>BR03SP230| codons 1-99
PQITLWQRPLVAIKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
NIAIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6K, K20R, V35T, T39K, I50V, V118I, K122E, I135V, S162C, E169D, K173A, Q174K, T200I, E203D, Q207E, R211K, F214L, V245Q, E248D, A272P, Q278N, T286A, E291D, V292I, I293V, E297A, S322T, Q334L  
>BR03SP230| codons 1-335
PISPIKTVPVKLKPGMDGPRVKQWPLTEEKIKALTEICKEMEKEGKISKVGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDIVI
YQYMDDLYVGSDLEIGQHRIKIDELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKNLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGLG

References
Author Title Citation
Rodrigues, R Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. J Clin Virol, 2005