Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 881506 | 881506 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 26 |
| 2 | AZT+ DDI+ 3TC+ NVP+ RTV | 34 |
| 3 | D4T+ 3TC+ NVP+ IDV | 118 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L76V | L10V, I13V, I15V, K20T, R41K, L63P, I64V, L89I |
| >881506| codons 1-99 PQITLWQRPVVTVKVGGQLTEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIKVRQYD QIPVEICGHKAIGTVVVGPTPVNIIGRNILTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K219E | G190A | A98G | E6D, K122E, I135T, V179I, Q207E, R211K |
| >881506| codons 1-250 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYVDDLYVASDLEIGQHRTKIEELREHLWKWGFYTPDEKHQKEPPFLWMGYELHPDKWT VQPIVLPEKD |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |