Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 881505 | 881505 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 61 |
| 2 | AZT+ DDC+ IDV | 13 |
| 3 | AZT+ 3TC+ IDV | 39 |
| 4 | DDI+ D4T+ IDV | 17 |
| 5 | D4T+ 3TC+ RTV+ SQV | 69 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L76V, I84V | L23I, F53L | L10I, I13V, I15V, L19V, K20R, M36I, I62V, L63P, I64V |
| >881505| codons 1-99 PQITLWQRPIVTVKVGGQVREAILDTGADDTVLEEINLPGRWKPKIIGGIGGLIKVRQYD QVPVEICGHKAIGTVVVGPTPVNVIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K49R, D121Y, K122E, D123E, I135T, E169K, K173E, I178M, T200A, E204D, H208Y |
| >881505| codons 1-253 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISRIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILKPFREQNPDMVI YQYVDDLYVGSDLEIGQHRAKIEDLRQYLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWT |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |