Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 881220 | 881220 | Spain | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ IDV | 8 |
| 2 | AZT+ DDI | 60 |
| 3 | D4T+ 3TC+ IDV | 13 |
| 4 | D4T+ 3TC+ SQV | 17 |
| 5 | D4T+ 3TC+ NVP | 101 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I | L10F | K14R, Q18H, N37D, R41K, L63P, A71T, I72T, Q92R, I93L |
| >881220| codons 1-99 PQITLWQRPFVTIRIGGHLKEALLDTGADDTVLEEMDLPGKWKPKIIGGIGGFIKVRQYD QIPIEICGHKTTGTVLVGPTPVNIIGRNLLTRLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | K103N | K49R, S68G, V90I, D123E, I135T, S162D, K166R, D177E, I178M, R211K |
| >881220| codons 1-226 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISRIGPENPYNTPV FAIKKKDGTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQDSMTRILEPFRKQNPEMVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLKWGFYTPDKKHQKEPP |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |