Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 881214 | 881214 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 65 |
| 2 | AZT+ DDI+ SQV | 56 |
| 3 | AZT+ 3TC+ IDV | 13 |
| 4 | D4T+ RTV+ SQV | 21 |
| 5 | NVP+ NFV | 52 |
| 6 | DDI+ D4T+ IDV | 41 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74I, L210W, T215Y | K219N | Y181C | K32Q, V35E, T39A, E40F, K43E, V118I, K122E, I135R, H208Y, R211K, K223E, L228H |
| >881214| codons 1-253 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIQALEEICAFLEEEGKISKIGPENPYNTPV FAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYMDDLYVGSDLEIGQHRTKIEELRQYLWKWGFYTPDNKHQEEPPFHWMGYELHPDKWT VQPIVLPEKDSWT |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | G73T | L10V, T12I, I15V, G16A, K20M, E35G, M36I, R41K, I62V, L63P, H69R, K70T |
| >881214| codons 1-99 PQITLWQRPVVIIKVAGQLMEALLDTGADDTVLEGINLPGKWKPKMIGGIGGFIKVRQYD QVPIEICGRTAITTVLVGPTPVNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |