Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 880920 | 880920 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 136 |
| 2 | DDI | 75 |
| 3 | DDC | 6 |
| 4 | AZT | 63 |
| 5 | AZT+ RTV | 27 |
| 6 | AZT+ 3TC+ IDV | 36 |
| 7 | D4T+ 3TC+ IDV | 27 |
| 8 | DDI+ D4T+ NVP+ NFV | 36 |
| 9 | DDI+ D4T+ EFV | 39 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | L33I | L10I, I13V, M36I, L63P, I64V | G27R |
| >880920| codons 1-99 PQITLWQRPIVTVKIGGQLKEALLDTRADDTVIEEINLPGRWKPKMIGGIGGFVKVRQYD QIPVEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, L210W, T215Y | K103N, Y181C, G190A | T27S, S48E, K166R, L228R |
| >880920| codons 1-246 PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALVEICTELEKEGKIEKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI CQYMDDLYVASDLEIGQHRTKIEELRQHLWRWGFYTPDKKHQKEPPFRWMGYELHPDKWT VQPIVL |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |