Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 880906 | 880906 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 38 |
| 2 | AZT+ DDI | 58 |
| 3 | AZT+ DDI+ SQV | 45 |
| 4 | D4T+ 3TC+ IDV | 44 |
| 5 | DDI+ D4T+ NVP+ NFV | 49 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, L210W, T215Y | K103N, Y181C | K20R, T39S, E44D, S48T, V60I, T69E, A98S, K102Q, V118I, K122E, D123S, I135T, R211K |
| >880906| codons 1-253 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICSELEKDGKITKIGPENPYNTPI FAIKKKNSEKWRKVVDFRELNKRTQDFWEVQLGIPHPSGLKQNKSVTVLDVGDAYFSIPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYMDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWT |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | T74P | L10I, I13V, I15V, K20M, M36I, D60E, I62V, L63P, A71I, I93L | R87S |
| >880906| codons 1-99 PQITLWQRPIVTVKVGGQLMEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFIKVRQYE QVPIEICGHKIIGPVLVGPTPVNVIGSNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |