Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 880904 | 880904 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 70 |
| 2 | D4T | 127 |
| 3 | DDI+ D4T | 8 |
| 4 | DDI | 14 |
| 5 | AZT+ 3TC+ RTV | 9 |
| 6 | AZT+ 3TC+ IDV | 40 |
| 7 | AZT+ 3TC+ SQV | 10 |
| 8 | D4T+ NVP+ NFV | 49 |
| 9 | DDI+ D4T+ NVP+ NFV | 18 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V | L24I, Q58E | L10I, K20I, E35D, L63Q, I64V, T74S |
| >880904| codons 1-99 PQITLWQRPIVTIKIGGQLIEALIDTGADDTVLEDMNLPGRWKPKIIGGIGGFVKVREYD QIQVEICGHKAIGSVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, T215F | K219Q | K103N, Y181C, G190A | K20R, V35R, T39A, K49Q, V60I, T69N, D123E, I135T, S162D, I202V, H221Y, L228H |
| >880904| codons 1-250 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALREICAELEKEGKISQIGPENPYNTPI FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPDIVI CQYMDDLYVASDLEIGQHRTKVEELRQHLLRWGFFTPDQKYQKEPPFHWMGYELHPDKWT VQPIVLPEKD |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |