Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 880814 | 880814 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 8 |
| 2 | DDI+ D4T | 60 |
| 3 | D4T+ 3TC+ SQV | 52 |
| 4 | D4T+ 3TC+ NFV | 33 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, K65R, Q151M | V75I, F116Y | K49R, I50V, V60I, S68G, T69I, K122E, I135T, I142M, T165I, D177E, F214L, V245M |
| >880814| codons 1-250 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISRVGPENPYNTPI FAIKRKDGIKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYYSVPL DEDFRKYTAFTIPSTNNETPGMRYQYNVLPMGWKGSPAIFQSSMIKILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | L23I, F53L, G73S | L10I, K20I, N37H, R41K, L63P, A71V, V77I |
| >880814| codons 1-99 PQITLWQRPIVTIKIGGQLIEAILDTGADDTVLEEMHLPGKWKPKIIGGIGGLIKVRQYD QIPIEICGHKVISTVLIGPTPVNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |