<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
880724 880724 Spain 1999 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ RTV+ SQV 56

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I84V V11I, L24I L10I, T12P, K14R, E35D, M36V, N37S, R41K, Q61E, L63P, A71T, I72V, I93L  
>880724| codons 1-99
PQITLWQRPIIPIRIGGQLKEALIDTGADDTVLEDVSLPGKWKPKMIGGIGGFIKVRQYD
EIPIEICGHKTVGTVLVGPTPVNVIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35I, S68G, V106I, I135T, S162C, G196E, T200A, E203G, Q207N, R211K  
>880724| codons 1-246
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIEQHRAKIGELRNHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVL

References
Author Title Citation
Tural, C Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. AIDS, 2002
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005