Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 880716 | 880716 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 104 |
| 2 | AZT+ DDC | 165 |
| 3 | AZT+ DDC+ 3TC+ IDV | 52 |
| 4 | D4T+ NVP+ NFV | 62 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I | Q58E, G73S | K20I, L63P, I64V, A71V, V77I, I93L |
| >880716| codons 1-99 PQITLWQRPLVTIKIGGQLIEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVREYD QIPVEICGHKVISTVLIGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, L210W, T215Y | K103N, Y181C, G190A | K43Q, K49R, V118I, D123E, I135L, S162D, Q174N, D177E, E194Q, G196E, T200A, I202V, R211K |
| >880716| codons 1-246 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEQEGKISRIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DKEFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKNNPEIVI CQYMDDLYVASDLQIEQHRAKVEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVL |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |