Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 880419 | 880419 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 8 |
| 2 | AZT+ DDC | 34 |
| 3 | AZT+ DDI | 4 |
| 4 | DDI+ D4T+ RTV | 13 |
| 5 | AZT+ 3TC | 13 |
| 6 | D4T+ 3TC+ SQV | 130 |
| 7 | AZT+ 3TC+ NVP+ NFV | 16 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | K20R, E35D, M36I, N37E, I62V, L63P, A71V, V77I, I93L |
| >880419| codons 1-99 PQITLWQRPLVTIKIGGQLREALLDTGADDTVLEDIELPGRWKPKMIGGIGGFVKVRQYD QVPIEICGHKVIGTVLIGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | K103N, Y181C | T39S, I142V, T200A, I202V, R211K, L228R |
| >880419| codons 1-250 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICSELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYVDDLYVGSDLEIGQHRAKVEELRQHLLKWGFYTPDKKHQKEPPFRWMGYELHPDKWT VQPIVLPEKD |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |