Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 880416 | 880416 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDC | 49 |
| 2 | AZT+ 3TC | 36 |
| 3 | D4T+ 3TC+ SQV | 19 |
| 4 | D4T+ 3TC+ IDV | 18 |
| 5 | D4T+ 3TC+ NFV | 14 |
| 6 | D4T+ 3TC+ SQV+ NFV | 79 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | G73T | L10I, K20I, E35D, N37D, Q61E, L63P, I64V, A71V, V77I |
| >880416| codons 1-99 PQITLWQRPIVTIKIGGQLIEALLDTGADDTVLEDMDLPGRWKPKIIGGIGGFIKVRQYD EIPVEICGHKVITTVLIGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K219R | E44D, V118I, K122E, I135T, T200I, E203D, H208Y, R211K, D218E |
| >880416| codons 1-250 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRIKIDELRQYLWKWGFYTPERKHQKEPPFLWMGYELHPDKWT VQPIVLPEKD |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |