Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 880415 | 880415 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | RTI | 343 |
| 2 | 3TC+D4T+SQV | 48 |
| 3 | 3TC+AZT+NFV | 73 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | T4S, T12K, K20I, L63P, I64V, T74S, I93L |
| >880415| codons 1-99 PQISLWQRPLVKIKIGGQLIEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QIPVEICGHKAIGSVLVGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, V75M, L210W, T215Y | Y188L | K20R, V21I, V60I, T69E, K103R, K122E, I135T, S162C, Q197E, R211K |
| >880415| codons 1-250 PISPIETVPVKLKPGMDGPRIKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPI FAIKKKNSERWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYMDDLLVGSDLEIGEHRTKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKD |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |