Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 880414 | 880414 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 35 |
| 2 | AZT+ 3TC | 19 |
| 3 | D4T+ 3TC+ IDV | 51 |
| 4 | DDI+ D4T+ RTV+ SQV | 20 |
| 5 | DDI+ D4T+ NVP+ NFV | 54 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | G73S | L10I, T12P, N37S, I62V, L63P, I66L, I72R, V77I, I93L, C95F |
| >880414| codons 1-99 PQITLWQRPIVPIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKIIGGIGGFIKVRQYD QVPIELCGHKARSTVLIGPTPVNVIGRNLMTQLGFTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K103N, Y181C | K20R, V35T, T39A, K122E, I135T, G196E, Q207K, R211A, H221Y |
| >880414| codons 1-246 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICAELEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYMDDLYVGSDLEIEQHRTKIEELRKHLWAWGFYTPDKKYQKEPPFLWMGYELHPDKWT VQPIVL |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |