<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
880309 880309 Spain 1999 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 165
2 3TC+ SQV 21
3 Unknown 4
4 DDI+ D4T+ RTV 82

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82T, L90M F53L L10I, I15V, E34Q, L63P, A71V  
>880309| codons 1-99
PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLQEMNLPGRWKPKMIGGIGGLVKVRQYD
QIPIEICGHKVIGTVLVGPTPTNIIGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L210W, T215Y       K43Q, E44D, V118I, D123E, I135T, D177E, Q207E, H208Y, R211K  
>880309| codons 1-246
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEQDGKISKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELREYLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVL

References
Author Title Citation
Tural, C Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. AIDS, 2002
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005