Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 880240 | 880240 | Spain | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | 4 |
| 2 | D4T+ 3TC+ IDV | 52 |
| 3 | DDI+ D4T+ NVP | 27 |
| 4 | DDI+ D4T+ EFV | 40 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K103N, Y181C | K43E, K49R, W88C, V118I, K122E, D123E, I135M, S162D, D177E, G196E, R211K, H221Y |
| >880240| codons 1-249 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEEGKISRIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DEEFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPEIVI CQYMDDLYVGSDLEIEQHRTKIEELRQHLWKWGFYTPDKKYQKEPPFLWMGYELHPDKWT VQPIVLPEK |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I | L10F | K14R, Q18H, N37D, R41K, L63P, A71T, I72T, Q92R, I93L |
| >880240| codons 1-99 PQITLWQRPFVTIRIGGHLKEALLDTGADDTVLEEMDLPGKWKPKIIGGIGGFIKVRQYD QIPIEICGHKTTGTVLVGPTPVNIIGRNLLTRLGCTLNF |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |