Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 880219 | 880219 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 208 |
| 2 | AZT+ DDC | 26 |
| 3 | AZT+ DDI | 26 |
| 4 | DDI+ D4T | 25 |
| 5 | D4T+ 3TC+ IDV | 17 |
| 6 | D4T+ 3TC+ SQV | 34 |
| 7 | DDI+ D4T+ NFV | 70 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | I13V, K20T, E35D, M36I, K45Q, I64V |
| >880219| codons 1-99 PQITLWQRPLVTVKIGGQLTEALLDTGADNTVLEDINLPGRWKPQMIGGIGGFIKVRQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, Q151M, T215F | F116Y, K219Q | K20R, V60I, T69N, V90I, S162H, R172K, H208Y, R211K |
| >880219| codons 1-250 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPI FAIKKKNSNRWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYYSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQHSMTKILEPFKKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQYLLKWGFFTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKD |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |