Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 347965 | 347965 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 52 |
| 2 | AZT+ DDI | 104 |
| 3 | D4T+ 3TC+ SQV | 144 |
| 4 | D4T+ 3TC+ IDV | 13 |
| 5 | 3TC+ ABC+ EFV | 21 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | G73S | K20V, E35D, M36I, D60E, I62V, L63P, H69K, A71V |
| >347965| codons 1-99 PQITLWQRPLVTIKIGGQLVEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYE QVPIEICGKKVISTVLVGPTPVNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74V, M184V, T215F | K219Q | G190S | V60I, K101Q, D123E, I135T, S162Y, V179I, E203D, R211K, L228H |
| >347965| codons 1-246 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIII YQYVDDLYVSSDLEIGQHRTKIDELRQHLLKWGFFTPDQKHQKEPPFHWMGYELHPDKWT VQPIVL |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |