Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 235720 | 235720 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDC | 37 |
| 2 | AZT+ DDC+ RTV | 2 |
| 3 | DDI+ D4T+ RTV | 136 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | L24I | L10I, I15V, K20R, E35D, M36I, R41K, L63P |
| >235720| codons 1-99 PQITLWQRPIVTIKVGGQLREALIDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R | K219Q | V35T, T39A, K49R, K122E, I142T, E169D, I178L, E203K |
| >235720| codons 1-250 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAEMEKEGKISRIGPENPYNTPV FAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDLVI YQYMDDLYVGSDLEIGQHRTKIKELRQHLLRWGFTTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKD |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |