Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 226575 | 226575 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 52 |
| 2 | AZT+ DDC | 300 |
| 3 | AZT+ 3TC+ IDV | 78 |
| 4 | D4T+ 3TC+ NFV | 53 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | I13V, E35D, M36I, N37H, R41K, Q58*, I62V, L63P |
| >226575| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADNTVLEDIHLPGKWKPKMIGGIGGFIKVR*YD QVPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, M184V, T215F | K219Q | V118I, K122E, D123G, I135M, I142V, G196E, Q207E, R211K, F214L |
| >226575| codons 1-246 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEGFRKYTAFTIPSMNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRTKIEELREHLLKWGLFTPDQKHQKEPPFLWMGYELHPDKWT VQPIVL |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |