Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 119733 | 119733 | Spain | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 117 |
| 2 | AZT+ DDC | 130 |
| 3 | AZT+ DDC+ IDV | 17 |
| 4 | D4T+ 3TC+ IDV | 117 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | L10I, K20M, E35D, M36I, I62V, L63P, I64V, I85V |
| >119733| codons 1-99 PQITLWQRPIVTIKIGGQLMEALLDTGADDTVLEDINLPGRWKPKLIGGIGGFVKVRQYD QVPVEICGHKAIGTVLVGPTPANIVGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | A62V | K20R, K43E, E44A, K166R, G196E, E203D, H208Y, K223Q, L228R |
| >119733| codons 1-246 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEEAGKISKIGPENPYNTPV FVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRTKIDELRQYLWRWGFYTPDKKHQQEPPFRWMGYELHPDKWT VQPIVL |
References
| Author | Title | Citation |
| Tural, C | Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |